Pulling from theories of social exchange, deonance, and fairness heuristics, this study focuses on the relationship between overall justice climate and both the prosocial and deviant behaviors of groups. Specifically, it considers two contextual boundary conditions on this effect—corporate social responsibility and group moral identity. Results from a laboratory experiment are presented, which show a significant effect for overall justice climate and a two-way interaction between overall justice climate and CSR on group-level prosocial and deviant behaviors, and a marginally significant (...) interaction of group moral identity with overall justice climate on group deviance. The implications of contextual influences on workplace ethics and justice are discussed. (shrink)

Cheating and rule violations in intercollegiate athletics continue to be relevant issues in many institutions of higher education because they reflect upon the integrity of the institutions in which they are housed, causing concern among many faculty members, administrators, and trustees. Although a great deal of research has documented the numerous rule violations in NCAA intercollegiate athletics, much of it has failed to combine sound theory with practical solutions. The purpose of this study was to examine the possible extensions of (...) the organizational justice framework to the problem of rule violations in intercollegiate athletics. In doing so, the current study examined (a) perceived areas of injustice among coaches at NCAA Division I institutions, (b) avenues by which coaches resolve these injustices, and (c) potential solutions for resolving injustices in an attempt to reduce NCAA violations. Six NCAA Division I basketball coaches from various parts of the country (four from men's teams and two from women's teams) were interviewed using a semi-structured format. Despite the NCAA's efforts to create parity, results showed that coaches perceived several areas of inequities in recruiting, including financial resources and academic standards. The interviewed coaches described several means that are currently used to resolve these inequities and offered recommendations for changes to reduce injustice in the future. (shrink)

The rapid advances in genomics over the last decade have come to fruition amid intense public discussions of justice in medicine and health care. While much emphasis has been placed on increasing diversity in genomics research participation, an overly narrow focus on recruitment eschews recognition of the disparities in health care that will ultimately shape access to the benefits of genomic medicine. In this essay, we suggest that achieving a just genomics, both now and in the future, requires an explicit (...) ELSI of translation—normative and pragmatic scholarship that embraces the interconnectedness of research and clinical care and centers the obligations of researchers, institutions, and funders to mitigate inequities throughout the translational pipeline. We propose core principles to guide an ELSI of translation and to ensure that this work balances the value of the generalizable knowledge that genomics research generates and the value of the individuals and communities who make this research possible. (shrink)

Each year individuals are required to execute millions of authorizations for the release of their health records as a condition of employment, applying for various types of insurance, and submitting claims for benefits. Generally, there are no restrictions on the scope of information released pursuant to these compelled authorizations, and the development of a nationwide system of interoperable electronic health records will increase the amount of health information released. After quantifying the extent of these disclosures, this article discusses why it (...) is important to limit disclosures of health information for nonmedical purposes as well as how it may be possible to do so. (shrink)

Indirect speech acts—responding “I forgot to wear my watch today” to someone who asked for the time—are ubiquitous in daily conversation, but are understudied in current neurobiological models of language. To comprehend an indirect speech act like this one, listeners must not only decode the lexical-semantic content of the utterance, but also make a pragmatic, bridging inference. This inference allows listeners to derive the speaker’s true, intended meaning—in the above dialog, for example, that the speaker cannot provide the time. In (...) the present work, we address this major gap by asking non-aphasic patients with behavioral variant frontotemporal dementia and brain-damaged controls with amnestic mild cognitive impairment to judge simple question-answer dialogs of the form: “Do you want some cake for dessert?” “I’m on a very strict diet right now,” and relate the results to structural and diffusion MRI. Accuracy and reaction time results demonstrate that subjects with bvFTD, but not MCI, are selectively impaired in indirect relative to direct speech act comprehension, due in part to their social and executive limitations, and performance is related to caregivers’ judgment of communication efficacy. MRI imaging associates the observed impairment in bvFTD to cortical thinning not only in traditional language-associated regions, but also in fronto-parietal regions implicated in social and executive cerebral networks. Finally, diffusion tensor imaging analyses implicate white matter tracts in both dorsal and ventral projection streams, including superior longitudinal fasciculus, frontal aslant, and uncinate fasciculus. These results have strong implications for updated neurobiological models of language, and emphasize a core, language-mediated social disorder in patients with bvFTD. (shrink)

DNA identification methods are such an established part of our law enforcement and criminal justice systems it is hard to believe that the technologies were developed as recently as the mid-1980s, and that the databases of law enforcement profiles were established in the 1990s. Although the first databases were limited to the DNA profiles of convicted rapists and murderers, the success of these databases in solving violent crimes provided the impetus for Congress and state legislatures to expand the scope of (...) the databases with little critical examination of each expansion's value to law enforcement or cost to privacy and civil liberties.We are now entering a new stage of DNA forensics, in which successive database expansions over the last decade have raised the possibility of creating a population-wide repository. In addition, new applications of DNA profiling, including familial and low stringency searches, have been added to DNA dragnets, the use of medical samples for forensic analysis, and other measures to create a series of crucial, yet largely unexplored, second-generation legal and policy issues. (shrink)

With the growth of precision medicine research on health data and biospecimens, research institutions will need to build and maintain long-term, trusting relationships with patient-participants. While trust is important for all research relationships, the longitudinal nature of precision medicine research raises particular challenges for facilitating trust when the specifics of future studies are unknown. Based on focus groups with racially and ethnically diverse patients, we describe several factors that influence patient trust and potential institutional approaches to building trustworthiness. Drawing on (...) these findings, we suggest several considerations for research institutions seeking to cultivate long-term, trusting relationships with patients: Address the role of history and experience on trust, engage concerns about potential group harm, address cultural values and communication barriers, and integrate patient values and expectations into oversight and governance structures. (shrink)

La «question de l'Inconditionné» est développée par Paul Tillich dans une Religionsphilosophie pensée comme Logique de la raison religieuse et comme Théorie du sens, dans une perspective théonome. La présente étude analyse le projet du premier Tillich, après l'avoir situé en relation au paradigme de la Modernité. Tillich mène un double combat, face à l'«hybris religieuse» de l'hétéronomie et à l'«hybris culturelle» de la pure autonomie. Partant de la tension fondamentale entre identité mystique et différence éthique, le projet de Tillich (...) souligne l'aspect paradoxal et dialectique de la religion, son vouloir d'atteindre le contenu inconditionné à travers des formes conditionnées, sa résistance à être pur objet et concept d'une science. Dépassant le paradigme de la Modernité, Tillich construit une Philosophie de la Religion située dans le système des sciences, mais non fondée sur le conditionné, mais au contraire sur l'Inconditionné. Les éléments et catégories du religieux sont soumis à l'analyse à travers un processus méthodologique complexe, critique et dialectique, intuitif et vital; est ainsi formulée l'unité de sens entre le fondé, le fondant et le fondement ultime qui soutient tout. La dialectique du sacré et du profane, du divin et du démoniaque, de la foi et de l'incrédulité, de Dieu et du monde, est éclairée dans la perspective théonome; d'où est surpassée la pure autonomie, en lutte avec l'hétéronomie religieus. (shrink)

Introduction Deep brain stimulation (DBS) is approved under a humanitarian device exemption to manage treatment-resistant obsessive-compulsive disorder (TR-OCD) in adults. It is possible that DBS may be trialed or used clinically off-label in children and adolescents with TR-OCD in the future. DBS is already used to manage treatment-resistant childhood dystonia. Evidence suggests it is a safe and effective intervention for certain types of dystonia. Important questions remain unanswered about the use of DBS in children and adolescents with TR-OCD, including whether (...) mental health clinicians would refer pediatric patients for DBS, and who would be a good candidate for DBS.Objectives To explore mental health clinicians’ views on what clinical and psychosocial factors they would consider when determining which children with OCD would be good DBS candidates.Materials and Methods In depth, semi-structured interviews were conducted with n = 25 mental health clinicians who treat pediatric patients with OCD. The interviews were transcribed, coded, and analyzed using thematic content analysis. Three questions focused on key, clinical, and psychosocial factors for assessing candidacy were analyzed to explore respondent views on candidacy factors. Our analysis details nine overarching themes expressed by clinicians, namely the patient’s previous OCD treatment, OCD severity, motivation to commit to treatment, presence of comorbid conditions, family environment, education on DBS, quality of life, accessibility to treatment, and patient age and maturity.Conclusions Clinicians generally saw considering DBS treatment in youth as a last resort and only for very specific cases. DBS referral was predominantly viewed as acceptable for children with severe TR-OCD who have undertaken intensive, appropriate treatment without success, whose OCD has significantly reduced their quality of life, and who exhibit strong motivation to continue treatment given the right environment. Appropriate safeguards, eligibility criteria, and procedures should be discussed and identified before DBS for childhood TR-OCD becomes practice. (shrink)

In a variety of synaesthesia, photisms result from affect-laden stimuli as emotional words, or faces of familiar people. For R, who participated in this study, the sight of a familiar person triggers a mental image of "a human silhouette filled with colour". Subjective descriptions of synaesthetic experiences induced by the visual perception of people's figures and faces show similarities with the reports of those who claim to possess the ability to see the aura. It has been proposed that the purported (...) auric perception may be easily explained by the presence of a specific subtype of cross-modal perception. We analyse the subjective reports of four synaesthetes who experience colours in response to human faces and figures. These reports are compared with descriptions of alleged auric phenomena found in the literature and with claims made by experts in esoteric spheres. The discrepancies found suggest that both phenomena are phenomenologically and behaviourally dissimilar. (shrink)

The article investigates the language of the faith of the Church on the mystery of God. It analyzes its origin and typology, its specificity and ecclesial meaning, its ecumenical relevance, its logical coherence and its theological actuality. It follows the definitions and declarations of the Magisterium while placing the doctrine within the bi-millennial history of Trinitarian theology. The study underlines the importance for the unity of the Church of the formulation of the faith which in adoring the inseparable Trinity proclaims (...) the Holy Monarchy - origin of the divine life and of the sacramental economy - of the eternal, unbegotten Father, principle of the whole deity. After having followed the efforts made by the first apologists to sketch out the language of the ineffable mystery, and the various models of trinitarian language, the study exposes the language used by the councils in East and West: Nicea I and II, Constantinople I to III, Lateran I to IV, Lyons II to Florence, Vatican I to II, so as better to formulate the principles which articulate the rule of faith of the Church. The logic of the ecclesial language is resumed in propositions concerned with the main affirmations of faith and the proclamation of the mystery. The first propositions treat the knowability of the mystery, the possibility of its verification and the dialectic of its language. The main propositions refer to the three divine hypostases, Father, Son and Spirit, in the economy of salvation and in. (shrink)

This study analyzes the meaning of the first article of faith: In the biblical message the unique and true God appears as the ultimate principle of all realities, as the object of the religious sense of all people, as the 'deus ignotus', creator of the universe and provident father of the human race, who, as the 'deus revelatus' manifests himself as the God of Israel, Lord of the covenant and Father of Jesus . Taking into account the Gospel message on (...) the all-powerful God as loving Father, the article studies the theological tradition of the Church, the symbol of whose faith begins with the words: Credo in unum Deum Patrem omnipotentem. God the Father emerges, in the affirmation of Denys of Rome, in the Symbol of the Apostles, in the faith of Nicea and in other documents of Church tradition, as the absolute and infinite reality, transcendant and personal, 'ingenitus aeternus', Principle without principle of the intrinsic divine life and of the history of salvation. The Church language, denying gnostic dualism, identifies the creator God of the old covenant with the merciful Father of the new salvific dispensation. Against patripatian Sabellianism the tradition affirms the distinction between the 'Pater ingenitus' and the only begotten Son. In order to overcome the challenges of modernity and the loss of consciousness regarding the difference between Creator and creature, the Councils of Vatican I and II remain faithful to the 'regula fide. (shrink)

A-theorists think there is a fundamental difference between the present and other times. This concern shows up in what kinds of properties they take to be instantiated, what objects they think exist and how they formalize their views. Nearly every contemporary A-theorist assumes that her metaphysics requires a tense logic – a logic with operators like and. In this paper, I show that there is at least one viable A-theory that does not require a logic with tense operators. And I (...) will argue that three common indispensability arguments for tense operators are unsound. (shrink)

Should you care less about your distant future? What about events in your life that have already happened? How should the passage of time affect your planning and assessment of your life? Most of us think it is irrational to ignore the future but harmless to dismiss the past. But this book argues that rationality requires temporal neutrality.

Timothy Williamson thinks that every object is a necessary, eternal existent. In defense of his view, Williamson appeals primarily to considerations from modal and tense logic. While I am uncertain about his modal claims, I think there are good metaphysical reasons to believe permanentism: the principle that everything always exists. B-theorists of time and change have long denied that objects change with respect to unqualified existence. But aside from Williamson, nearly all A-theorists defend temporaryism: the principle that there are temporary (...) existents. I think A-theorists are better off without this added commitment, but I will not argue for that in any great detail here. Instead, I will contend that a very tempting A-theoretic argument for temporaryism is unsound. In the first half of the paper, I will develop the Moorean “common sense” argument for temporaryism and dispute its central premise, namely that temporaryism is a valid generalization from highly plausible beliefs about change. I will argue that given the pervasive vagueness in our ordinary beliefs about change and the background commitments of all A-theories, no party can claim to be the common sense view because no party can accommodate most of our common sense beliefs about change in existence. In the second half of the paper, I will propose a permanentist A-theory that explains all change over time as a species of property change. I call it the minimal A-theory, since it dispenses with the change in existence assumption. As we'll see, the permanentist alternative performs well enough in explaining our ordinary beliefs about change, and it has better prospects for answering some objections commonly levied against A-theories. (shrink)

Background Machine learning (ML) is utilized increasingly in health care, and can pose harms to patients, clinicians, health systems, and the public. In response, regulators have proposed an approach that would shift more responsibility to ML developers for mitigating potential harms. To be effective, this approach requires ML developers to recognize, accept, and act on responsibility for mitigating harms. However, little is known regarding the perspectives of developers themselves regarding their obligations to mitigate harms.Methods We conducted 40 semi-structured interviews with (...) developers of ML predictive analytics applications for health care in the United States.Results Participants varied widely in their perspectives on personal responsibility and included examples of both moral engagement and disengagement, albeit in a variety of forms. While most (70%) of participants made a statement indicative of moral engagement, most of these statements reflected an awareness of moral issues, while only a subset of these included additional elements of engagement such as recognizing responsibility, alignment with personal values, addressing conflicts of interests, and opportunities for action. Further, we identified eight distinct categories of moral disengagement reflecting efforts to minimize potential harms or deflect personal responsibility for preventing or mitigating harms.Conclusions These findings suggest possible facilitators and barriers to the development of ethical ML that could act by encouraging moral engagement or discouraging moral disengagement. Regulatory approaches that depend on the ability of ML developers to recognize, accept, and act on responsibility for mitigating harms might have limited success without education and guidance for ML developers about the extent of their responsibilities and how to implement them. (shrink)

The purpose of this study is to investigate the role of school principal trustworthiness components (i.e., ability, integrity, benevolence) in helping shape teacher trust and affective commitment within schools. Using data from 1,026 teachers in Spain and structural equation modeling (via EQS 6.3), this study establishes how a principal’s integrity and benevolence are key in determining, both directly and indirectly (via trust in the principal), teachers’ affective commitment to their school. It also reveals that the perceived ability of a principal (...) is not effective in generating trust or affective commitment to the school in teachers. As a contribution to the literature, these findings reveal that the ethical trustworthiness (benevolence, integrity) of principals is key in engendering trust and affective commitment to schools. Thus, to shape work environments that are high in trust and commitment, principals should focus on behaving in ways that make their integrity and benevolence manifest to their teachers. (shrink)

Many studies focused on the letter and sound co-occurrences to account for the well-documented syllable-based effects in French in visual (pseudo)word processing. Although these language-specific statistical properties are crucial, recent data suggest that studies which go all-in on phonological and orthographic regularities may be misguided in interpreting how – and why – readers locate syllable boundaries and segment clusters. Indeed, syllable-based effects could depend on more abstract, universal phonological constraints that rule and govern how letter and sound occur and co-occur, (...) and readers could be sensitive to sonority – a universal phonological element – for processing (pseudo)words. Here, we investigate whether French adult skilled readers rely on universal phonological sonority-related markedness continuum across the syllable boundaries for segmentation (e.g., from marked, illegal intervocalic clusters /zl/ to unmarked, legal intervocalic clusters /lz/). To address this question, we ran two tasks with 128 French adult skilled readers using two versions of the illusory conjunction paradigm (Task 1 without white noise; Task 2 with white noise). Our results show that syllable location and segmentation in reading is early and automatically modulated by phonological sonority-related markedness in the absence or quasi-absence of statistical information, and does not require acoustic-phonetic information. We discuss our results towards the overlooked role of phonological universals and the over-trusted role of statistical information during reading processes. (shrink)

The work of Sankary et al. (2022) provides valuable insights into the experiences of participants exiting brain device research. Empirical bioethics research such as this is critical to understandi...

Philosophers like to worry about luck. And well they should. Luck poses potential difficulties for knowledge, moral appraisal, and freedom. The primary target of this paper will be the last of these concerns . Recent arguments from luck have been levied against libertarian accounts of free will, including agent-causal ones. One general goal of this paper will be to demonstrate the truth of an often overlooked claim about responsibility-undermining luck. Part of this task will include illustrating what is genuinely worrisome (...) about luck in the context of free will. It will turn out that the problem is not fundamentally a problem of explanation. Another aim will be to argue that the truth of this claim about luck reveals a problem for event-causal libertarianism but has yet to reveal a problem for the agent-causal view. For the purposes of this paper, it will be assumed that luck does indeed undermine free action and moral responsibility. But it will be argued that agent-caused actions have not been shown to be "lucky.". (shrink)

Pierre Duhem’s philosophy of science was criticized by several of his contemporaries for being surreptitiously influenced by his Catholic faith. In his essay “Physics of a Believer,” Duhem defends himself against this appraisal. In this paper, I detail Duhem’s argument and reconstruct his view concerning the relationship between theoretical science and religious belief. Ultimately, Duhem claims that the propositions of physical theory cannot contradict the propositions of religious belief because they do not share a domain of reference. To clarify why (...) Duhem holds this view, I present a case study: the discovery of entropy. By examining how the term “entropy” was introduced into thermo-dynamic theory, a story with which Duhem was intimately familiar, much of the apparent conflict in Duhem’s philosophy of science is resolved. (shrink)

Protein misfolding is a topic that is of primary interest both in biology and medicine because of its impact on fundamental processes and disease. In this review, we revisit the concept of protein misfolding and discuss how the field has evolved from the study of globular folded proteins to focusing mainly on intrinsically unstructured and often disordered regions. We argue that this shift of paradigm reflects the more recent realisation that misfolding may not only be an adverse event, as originally (...) considered, but also may fulfil a basic biological need to compartmentalise the cell with transient reversible granules. We nevertheless provide examples in which structure is an important component of a much more complex aggregation behaviour that involves both structured and unstructured regions of a protein. We thus suggest that a more comprehensive evaluation of the mechanisms that lead to aggregation might be necessary. (shrink)

Rare genetic diseases collectively impact millions of individuals in the United States. These patients and their families share many challenges including delayed diagnosis, lack of knowledgeable providers, and limited economic incentives to develop new therapies for small patient groups. As such, rare disease patients and families often must rely on advocacy, including both self-advocacy to access clinical care and public advocacy to advance research. However, these demands raise serious concerns for equity, as both care and research for a given disease (...) can depend on the education, financial resources, and social capital available to the patients in a given community. In this article, we utilize three case examples to illustrate ethical challenges at the intersection of rare diseases, advocacy and justice, including how reliance on advocacy in rare disease may drive unintended consequences for equity. We conclude with a discussion of opportunities for diverse stakeholders to begin to address these challenges. (shrink)

L'étude aborde la question de la méthode théologique, en considérant sa nature et sa typologie, ses possibilités et ses limites, ainsi que les conditions de sa légitimité devant les instances du «depositum fidei». On attribue une importance spéciale à la tension de fond entre l'usage de la méthode kérygmatique et de la méthode dialogale dans la théologie du passé, mais surtout dans le débat actuel, spécialement entre divers courants de la théologie de la transcendance, telles les «théologies de la parole» (...) et la «méthode de corrélation», ou encore entre les «théologies du mystère» et la «méthode transcendantale». Pareille tension s'aggrave dans les «théologies de l'immanence», telles les théologies de la «mort de Dieu» ou les «théologies de l'histoire», ou entre les «théologies de la modernité» et certaines «théologies de la praxis». A la fin de ce panorama du pluralisme méthodologique actuel, on formule certains principes fondamentaux sur le problème débattu. Finalement, on considère le caractère obligatoire du «depositum fidei» comme instance théologique définitive. (shrink)

Various authors have attempted to understand knowledge-wh—or knowledge ascriptions that include an interrogative complement. I present and explain some of the analyses offered so far and argue that each view faces some problems. I then present and explain a newanalysis of knowledge-wh that avoids these problems and that offers several other advantages. Finally I raise some problems for invariantism about knowledge-wh and I argue thatcontextualism about knowledge-wh fits nicely with a very natural understanding of the nature of questions.